The city within a city, the Vatican is a must see on anyone's Rome holiday check list. with a luxury Rome vacation apartment from Italy Unique, stay near Vatican City to explore the Vatican's stunning architecture, museums, history and mystique. Off the beaten path in Rome. Take a break from the tourist cues for a unique stroll around Borgo Pio, the nearby neighborhood that seems worlds away from Catholicism, deep in Roman tradition continuing to preside over peaceful back alleys.